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J1442
Filgrastim
Brand: NeupogenGeneric: Filgrastim Amgen
NDC (11-digit)
00006-0278-02
NDC (10-digit)
0006-0278-02
UOM
UN
JW/JZ Modifier
Required
Important: NDC billing requirements vary by payer and are updated periodically. Always verify with current CMS guidelines, payer-specific NDC policies, and the FDA NDC Directory. This information is for educational purposes only and does not guarantee payment or coding accuracy.
NDC Structure
Labeler Code
00006
Manufacturer/Labeler
Product Code
0278
Drug Product
Package Code
02
Package Size
Package SizeSingle-use vial
Dosage FormInjection, solution
Strength300 mcg / mL
RouteSubcutaneous (SC) / Intravenous (IV)
10-digit NDC0006-0278-02
11-digit NDC00006-0278-02
Unit of MeasureUN
Units per HCPCS480 mcg per unit
Code Relationships
HCPCS / J Codes
J1442
J Codes
J1442
Common CPT Relationships
9637296374
Typical Specialties
OncologyHematology
Documentation Requirements
- Diagnosis supporting medical necessity (e.g., neutropenia)
- Dose administered and route (SC or IV)
- NDC in 11-digit format on claim
- JW or JZ modifier for single-use vial
Common Billing Mistakes
- Confusing Neupogen (J1442) with Neulasta (J1449)
- Incorrect unit calculation (J1442 = 480 mcg per unit)
- Missing JW or JZ modifier for single-use vial
Common Denials & Rejections
Denials
- CO-50: Not medically necessary
- CO-16: Missing or invalid NDC
Rejections
- NDC format error
- Missing JW/JZ modifier
- Wrong J-code (Neupogen vs Neulasta)
Related CARC Codes
CO-50CO-16
Related RARC Codes
N130
Related Modifiers
JWJZ
Quick Actions
Related Payer Policies
- Medicare covers for chemotherapy-induced neutropenia
- Verify biosimilar vs originator billing rules