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J9035
Bevacizumab
Brand: AvastinGeneric: Bevacizumab Genentech
NDC (11-digit)
31747-0591-01
NDC (10-digit)
31747-591-01
UOM
ML
JW/JZ Modifier
Required
Important: NDC billing requirements vary by payer and are updated periodically. Always verify with current CMS guidelines, payer-specific NDC policies, and the FDA NDC Directory. This information is for educational purposes only and does not guarantee payment or coding accuracy.
NDC Structure
Labeler Code
31747
Manufacturer/Labeler
Product Code
0591
Drug Product
Package Code
01
Package Size
Package SizeSingle-use vial, 16 mL
Dosage FormInjection, solution
Strength400 mg / 16 mL
RouteIntravenous (IV)
10-digit NDC31747-591-01
11-digit NDC31747-0591-01
Unit of MeasureML
Units per HCPCS10 mg per unit
Code Relationships
HCPCS / J Codes
J9035
J Codes
J9035
Common CPT Relationships
96413964159636596366
Typical Specialties
OncologyOphthalmologyGynecology
Documentation Requirements
- Diagnosis supporting medical necessity (e.g., metastatic colorectal cancer)
- Dose administered and route (IV)
- Start and stop times for infusion
- NDC in 11-digit format on claim
- JW or JZ modifier for single-use vial
Common Billing Mistakes
- Submitting NDC in 10-digit format instead of 11-digit
- Incorrect unit calculation (J9035 = 10 mg per unit, not 1 mg)
- Missing JW or JZ modifier for single-use vial
- NDC does not match the product actually administered
- Missing infusion start/stop times in documentation
Common Denials & Rejections
Denials
- CO-16: Missing or invalid NDC
- CO-50: Not medically necessary for diagnosis
- CO-97: Drug bundled into chemotherapy administration
- N130: Service not covered for this diagnosis
Rejections
- NDC format error (must be 11-digit 5-4-2)
- Missing JW/JZ modifier on single-use vial claim
- Units exceed expected range for diagnosis
Related CARC Codes
CO-16CO-50CO-97CO-11
Related RARC Codes
N130N522M144
Related Modifiers
JWJZ2559
Quick Actions
Related Payer Policies
- Medicare NCD for bevacizumab (off-label use rules)
- Most payers require NDC + JW/JZ for Part B
- Commercial payers may require prior authorization for off-label uses